Cyclodextrin

Author: Technical Panel

Date

28/02/2006

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540

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Nutrient Deliver Aid

WHAT IS A CYCLODEXTRIN?

Cyclodextrin complexes involve coating fat soluble compounds (namely pro hormones) with a carbohydrate that supposedly makes the compound more soluble, particularly in oral mucosa or membranes of the mouth. The idea for this type of delivery is based on recent preliminary studies showing that this type of drug delivery system mayallow a more efficient oral delivery system for testosterone, therby obviating the need for testosterone injections.

Cyclodextrin technology is very difficult to get right and only a fraction of manufacturers know truly what they are doing. Some ill- conceived cyclodextrin processes tend to permit dissociation of the compound from the matrix. Hydroxy-Propyl Beta Cyclodextrin LPJ Research is known to be the leader when it comes to cyclodextrin complexes and the only one that has been proven to be successful in enhacing solubility.

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